Manchester United centre-back Timothy Fosu-Mensah is expected to miss the rest of the season after picking up an injury in Thursday's Manchester derby.
Bournemouth will have to do without Dan Gosling and Andrew Surman for Saturday's visit to the Stadium of Light.
Southampton's injury list is about to get two names short as both striker Charlie Austin and defender Matt Targett are back in full training.
Manchester United defenders Eric Bailly and Daley Blind may be forced to start for their side again on Sunday against Swansea.
Manchester United captain Wayne Rooney may return to his side's starting XI to face Swansea on Sunday.
Manchester United midfielder Marouane Fellaini will be suspended for his sides next three league matches.
Arsenal manager Arsene Wenger confirmed that winger Alex Oxlade-Chamberlain is fit enough to start against Spurs on Sunday.
Sitting in 20th place, Sunderland looked doomed for relegation already, but a growing list of weekend doubts won't help its morale.
Slaven Bilic has confirmed that Andy Carroll will miss out on Saturday's trip to Stoke City due to a thigh problem.
Steve Agnew has confirmed that both Dani Ayala and Grant Leadbitter are doubtful for Sunday's match against Manchester City at the Riverside Stadium.
Leicester City striker Islam Slimani returned to training on Thursday and could feature against West Brom at the Hawthorns on Saturday.
Craig Cathcart watch continues as the center back continues to try to recover from a knee injury, this time with the visit of Liverpool as the target return date.
Laurent Koscielny is more likely to miss out than play as Arsenal and Spurs face off this Sunday in a crucial North London Derby for both sides.
Salomon Rondon will return to the West Brom starting line-up due to a hamstring injury suffered by his replacement Hal Robson-Kanu.
Hal Robson-Kanu, a starter recently due to Salomon Rondon's poor form, will miss Week 34 after injuring his hamstring early this week in training.